VEGF-A, a key role
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VEGF-A, a key role
Friday, 12 December 2008 17:18
Research news
An Italian team demonstrates the key role of a cytokine of angiogenesis : the VEGF-A.
Formation of new blood vessels, called angiogenesis, systematically accompanies a chronic inflammatory response. This angiogenesis allows recruitment of cellular and non cellular transmitters of inflammation. This Italian team shows the key role of a cytokine of angiogenesis, the VEGF-A: its expression is significantly increased among patients with IBD and contributes to inflammation. These discoveries make VEGF-A a new potential therapeutic target for the treatment of RCH.
(Scaldaferri et al, Gastroenterology 2008; in press)
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